Biólogo Ambiental, Magíster en Bioestadística y en Ciencias Biológicas mención Ecología y Biología Evolutiva de la Universidad de Chile. Actualmente cursando Doctorado en Metodología de la Investigación Biomédica y Salud Pública en la Universitat Autònoma de Barcelona siendo parte del Research group on Psychosocial risks, Organization of Work and Health (POWAH-UAB). Desde 2020 se desempeña como estadístico en CIAPEC.
Cargo:
Asistente de Investigación Estadístico
Pedro Felipe Ferrer Rosende
Publicaciones
2024
Ferrer, Pedro; Garmendia, María Luisa
Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy Artículo de revista
En: Journal of pediatric gastroenterology and nutrition, 79(2), 371–381, 2024.
@article{nokey,
title = {Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy},
author = {Pedro Ferrer and María Luisa Garmendia},
doi = {https://doi.org/10.1002/jpn3.12294},
year = {2024},
date = {2024-08-05},
journal = {Journal of pediatric gastroenterology and nutrition, 79(2), 371–381},
abstract = {- Otros autores: Valeria De Toro, Gigliola Alberti, Angelica Dominguez, Karina Carrasco-Negüe, Rodrigo Valenzuela, Paola Casanello.
- Cómo citar: De Toro, V., Alberti, G., Dominguez, A., Carrasco-Negüe, K., Ferrer, P., Valenzuela, R., Garmendia, M. L., & Casanello, P. (2024). Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy. Journal of pediatric gastroenterology and nutrition, 79(2), 371–381. https://doi.org/10.1002/jpn3.12294
- Resumen: Background: Previous studies of maternal docosahexaenoic acid (DHA) supplementation during pregnancy have controversial and contrasting results on the short and long-term effects on early child growth. The impact of this nutritional intervention on the postnatal growth patterns in the offspring of women with pregestational overweight/obesity (PGO) also remains controversial.
Objective: To analyze the postnatal growth patterns during the first 4 months of life in the offspring of women with PGO randomly supplemented with 800 mg/day (PGO-800) compared with normative doses of 200 mg/day (PGO-200) of DHA during pregnancy (<15 weeks of gestation until delivery).},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
- Otros autores: Valeria De Toro, Gigliola Alberti, Angelica Dominguez, Karina Carrasco-Negüe, Rodrigo Valenzuela, Paola Casanello.
- Cómo citar: De Toro, V., Alberti, G., Dominguez, A., Carrasco-Negüe, K., Ferrer, P., Valenzuela, R., Garmendia, M. L., & Casanello, P. (2024). Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy. Journal of pediatric gastroenterology and nutrition, 79(2), 371–381. https://doi.org/10.1002/jpn3.12294
- Resumen: Background: Previous studies of maternal docosahexaenoic acid (DHA) supplementation during pregnancy have controversial and contrasting results on the short and long-term effects on early child growth. The impact of this nutritional intervention on the postnatal growth patterns in the offspring of women with pregestational overweight/obesity (PGO) also remains controversial.
Objective: To analyze the postnatal growth patterns during the first 4 months of life in the offspring of women with PGO randomly supplemented with 800 mg/day (PGO-800) compared with normative doses of 200 mg/day (PGO-200) of DHA during pregnancy (<15 weeks of gestation until delivery).
- Cómo citar: De Toro, V., Alberti, G., Dominguez, A., Carrasco-Negüe, K., Ferrer, P., Valenzuela, R., Garmendia, M. L., & Casanello, P. (2024). Growth patterns in infants born to women with pregestational overweight/obesity supplemented with docosahexaenoic acid during pregnancy. Journal of pediatric gastroenterology and nutrition, 79(2), 371–381. https://doi.org/10.1002/jpn3.12294
- Resumen: Background: Previous studies of maternal docosahexaenoic acid (DHA) supplementation during pregnancy have controversial and contrasting results on the short and long-term effects on early child growth. The impact of this nutritional intervention on the postnatal growth patterns in the offspring of women with pregestational overweight/obesity (PGO) also remains controversial.
Objective: To analyze the postnatal growth patterns during the first 4 months of life in the offspring of women with PGO randomly supplemented with 800 mg/day (PGO-800) compared with normative doses of 200 mg/day (PGO-200) of DHA during pregnancy (<15 weeks of gestation until delivery).
Ferrer, Pedro; Pereira, Ana
Post menarcheal growth patterns in a contemporary cohort of Latino girls Artículo de revista
En: Horm. Res. Paediatr., 2024.
@article{nokey,
title = {Post menarcheal growth patterns in a contemporary cohort of Latino girls},
author = {Pedro Ferrer and Ana Pereira },
doi = {doi: 10.1159/000536506},
year = {2024},
date = {2024-01-22},
journal = {Horm. Res. Paediatr.},
abstract = {- Otros autores: Gaete X, Mericq V.
- Cómo citar:
- Resumen: Introduction: Menarche is the last stage of pubertal development, which coincides with the completion of longitudinal growth. As a consequence of the lack of national and up-to-date data related to post-menarcheal (PM) growth, the aim of our work was to evaluate post menarcheal growth in a group of contemporary healthy Chilean girls followed, prospectively, until 4 years post-menarche. Methods: This study was nested within the GOCS cohort, in a prospective fashion. The girls were followed yearly after menarche for at least four years. We modeled each girl growth using a Super Imposition by Translation and Rotation (SITAR) model. Results: A total of 534 girls were evaluated prospectively, 399 girls had height measured two years after menarche, 421 after three years, and 364 of 534 had height measured at four year post menarche. Expected height gained PM, in the complete study group was 6.6 ± 2.5 cm. We observed that the largest gain in height occurred after the first year PM (3.8 1.5 cm). According to the age of menarche, the group with earlier menarche (< 11 years old ) had a greater height gain in cm after four years PM ( 8.2± 3.2 cm ) and the smallest gain was among girls with menarche at an age older than 13 yr (4.4±1.6) ( p<0.001). Age at menarche was significantly associated with all post menarche growth patterns (size, timing and intensity), indicating that girls with older age at menarche grew taller, later and slower than girls with younger age at menarche. Adjusting PM growth pattern by BMI maintained all these association. Applying the SITAR model specifically , girls experiencing menarche after the age of 13 years exhibited slower growth , occurring slightly earlier and with less intensity when adjusted by BMI at menarche . Conclusion: In a national and updated dataset we observed that girls grew until 4 years post menarche an average of 6.6 ± 2.5 cm., with greatest gain occurring in the first year PM , (3.8 ± 1.5 cm). Age at menarche was associated with menarche growth patterns.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
- Otros autores: Gaete X, Mericq V.
- Cómo citar:
- Resumen: Introduction: Menarche is the last stage of pubertal development, which coincides with the completion of longitudinal growth. As a consequence of the lack of national and up-to-date data related to post-menarcheal (PM) growth, the aim of our work was to evaluate post menarcheal growth in a group of contemporary healthy Chilean girls followed, prospectively, until 4 years post-menarche. Methods: This study was nested within the GOCS cohort, in a prospective fashion. The girls were followed yearly after menarche for at least four years. We modeled each girl growth using a Super Imposition by Translation and Rotation (SITAR) model. Results: A total of 534 girls were evaluated prospectively, 399 girls had height measured two years after menarche, 421 after three years, and 364 of 534 had height measured at four year post menarche. Expected height gained PM, in the complete study group was 6.6 ± 2.5 cm. We observed that the largest gain in height occurred after the first year PM (3.8 1.5 cm). According to the age of menarche, the group with earlier menarche (< 11 years old ) had a greater height gain in cm after four years PM ( 8.2± 3.2 cm ) and the smallest gain was among girls with menarche at an age older than 13 yr (4.4±1.6) ( p<0.001). Age at menarche was significantly associated with all post menarche growth patterns (size, timing and intensity), indicating that girls with older age at menarche grew taller, later and slower than girls with younger age at menarche. Adjusting PM growth pattern by BMI maintained all these association. Applying the SITAR model specifically , girls experiencing menarche after the age of 13 years exhibited slower growth , occurring slightly earlier and with less intensity when adjusted by BMI at menarche . Conclusion: In a national and updated dataset we observed that girls grew until 4 years post menarche an average of 6.6 ± 2.5 cm., with greatest gain occurring in the first year PM , (3.8 ± 1.5 cm). Age at menarche was associated with menarche growth patterns.
- Cómo citar:
- Resumen: Introduction: Menarche is the last stage of pubertal development, which coincides with the completion of longitudinal growth. As a consequence of the lack of national and up-to-date data related to post-menarcheal (PM) growth, the aim of our work was to evaluate post menarcheal growth in a group of contemporary healthy Chilean girls followed, prospectively, until 4 years post-menarche. Methods: This study was nested within the GOCS cohort, in a prospective fashion. The girls were followed yearly after menarche for at least four years. We modeled each girl growth using a Super Imposition by Translation and Rotation (SITAR) model. Results: A total of 534 girls were evaluated prospectively, 399 girls had height measured two years after menarche, 421 after three years, and 364 of 534 had height measured at four year post menarche. Expected height gained PM, in the complete study group was 6.6 ± 2.5 cm. We observed that the largest gain in height occurred after the first year PM (3.8 1.5 cm). According to the age of menarche, the group with earlier menarche (< 11 years old ) had a greater height gain in cm after four years PM ( 8.2± 3.2 cm ) and the smallest gain was among girls with menarche at an age older than 13 yr (4.4±1.6) ( p<0.001). Age at menarche was significantly associated with all post menarche growth patterns (size, timing and intensity), indicating that girls with older age at menarche grew taller, later and slower than girls with younger age at menarche. Adjusting PM growth pattern by BMI maintained all these association. Applying the SITAR model specifically , girls experiencing menarche after the age of 13 years exhibited slower growth , occurring slightly earlier and with less intensity when adjusted by BMI at menarche . Conclusion: In a national and updated dataset we observed that girls grew until 4 years post menarche an average of 6.6 ± 2.5 cm., with greatest gain occurring in the first year PM , (3.8 ± 1.5 cm). Age at menarche was associated with menarche growth patterns.
2023
Pemjean, Isabel; Mediano, Fernanda; Ferrer, Pedro; Garmendia, María Luisa; Corvalán, Camila
Food access, domestic environments, and dietary quality of low-middle income Chilean children during the COVID-19 pandemic Artículo de revista
En: Front. Public Health, 2023.
@article{nokey,
title = {Food access, domestic environments, and dietary quality of low-middle income Chilean children during the COVID-19 pandemic},
author = {Isabel Pemjean and Fernanda Mediano and Pedro Ferrer and María Luisa Garmendia and Camila Corvalán },
doi = {doi: 10.3389/fpubh.2023.1164357},
year = {2023},
date = {2023-06-19},
urldate = {2023-06-19},
journal = {Front. Public Health},
abstract = {- Otros autores: Pemjean I.
- Cómo citar: Pemjean I, Mediano F, Ferrer P, Garmendia ML, Corvalán C. Food access, domestic environments, and dietary quality of low-middle income Chilean children during the COVID-19 pandemic. Front. Public Health. 2023;11:1164357. doi: 10.3389/fpubh.2023.1164357. PMID: 37408742. PMCID: PMC10319070. ISSN: 2296-2565. IF [JCR]: 5.2. Q1
- Resumen: Introduction: Food access is associated with dietary quality; however, people living in similar physical environments can have different food access profiles. Domestic environments may also influence how food access relates to dietary quality. We studied food access profiles of 999 low-middle income Chilean families with children during the COVID-19 lockdown and how these profiles relate to dietary quality; secondarily, we also explore the role of the domestic environment in this relationship.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
- Otros autores: Pemjean I.
- Cómo citar: Pemjean I, Mediano F, Ferrer P, Garmendia ML, Corvalán C. Food access, domestic environments, and dietary quality of low-middle income Chilean children during the COVID-19 pandemic. Front. Public Health. 2023;11:1164357. doi: 10.3389/fpubh.2023.1164357. PMID: 37408742. PMCID: PMC10319070. ISSN: 2296-2565. IF [JCR]: 5.2. Q1
- Resumen: Introduction: Food access is associated with dietary quality; however, people living in similar physical environments can have different food access profiles. Domestic environments may also influence how food access relates to dietary quality. We studied food access profiles of 999 low-middle income Chilean families with children during the COVID-19 lockdown and how these profiles relate to dietary quality; secondarily, we also explore the role of the domestic environment in this relationship.
- Cómo citar: Pemjean I, Mediano F, Ferrer P, Garmendia ML, Corvalán C. Food access, domestic environments, and dietary quality of low-middle income Chilean children during the COVID-19 pandemic. Front. Public Health. 2023;11:1164357. doi: 10.3389/fpubh.2023.1164357. PMID: 37408742. PMCID: PMC10319070. ISSN: 2296-2565. IF [JCR]: 5.2. Q1
- Resumen: Introduction: Food access is associated with dietary quality; however, people living in similar physical environments can have different food access profiles. Domestic environments may also influence how food access relates to dietary quality. We studied food access profiles of 999 low-middle income Chilean families with children during the COVID-19 lockdown and how these profiles relate to dietary quality; secondarily, we also explore the role of the domestic environment in this relationship.
Pereira, Ana; Ferrer, Pedro; Corvalán, Camila
Association between markers of adiposity during childhood and puberty onset in Latino girls Artículo de revista
En: J. Clin. Endocrinol. Metab., 2023.
@article{nokey,
title = {Association between markers of adiposity during childhood and puberty onset in Latino girls},
author = {Ana Pereira and Pedro Ferrer and Camila Corvalán},
doi = {doi: 10.1210/clinem/dgad294},
year = {2023},
date = {2023-06-05},
urldate = {2023-06-05},
journal = {J. Clin. Endocrinol. Metab.},
abstract = {- Otros autores: Binder A, Rojas J, Michels K, Mericq V.
- Cómo citar: Pereira A, Ferrer P, Binder A, Rojas J, Michels K, Corvalán C, Mericq V. Association between markers of adiposity during childhood and puberty onset in Latino girls. J. Clin. Endocrinol. Metab. 2023;dgad294. Online ahead of print. doi: 10.1210/clinem/dgad294. PMID: 37226986. ISSN: 0021-972X. IF [JCR]: 5.8. Q1
- Resumen: Context: Prepubertal adiposity is associated with earlier puberty. It is unclear when this association starts, if all adiposity markers are similarly associated, and whether all pubertal milestones are similarly affected.
Objective: To evaluate the association between different adiposity markers during childhood and the timing of different pubertal milestones in Latino girls.
Design, setting and participants: Longitudinal follow-up of 539 female participants of the Chilean Growth and Obesity Cohort (GOCS) recruited from childcare centers (mean age 3.5y) from the South East area of Santiago, Chile. Participants were singletons born between 2002-2003 within the normal birthweight range. Since 2006, a trained dietitian measured weight, height, waist circumference (WC) and skinfolds to estimate BMI CDC percentiles, central obesity, fat mass (%FM) and fat mass index (FMI = fat mass/height2).
Main outcome: since 2009, sexual maturation was assessed every 6 months to assess age at: i) thelarche, ii) pubarche, iii) menarche, and iv) age at peak height velocity (PHV).
Results: At thelarche, 12.5% were obese and 2% had central obesity. The median age of pubarche, menarche, and PHV were all associated with markers of adiposity at different time points during childhood; whereas thelarche only with %FM and FMI. Adiposity clusters models showed that children with trajectories of high WC, %FM and FMI during childhood were related with earlier thelarche, pubarche, menarche and PHV; BMI trajectories only with menarche and PHV.
Conclusions: Higher WC, %FM and FMI were associated with earlier age at thelarche, pubarche, menarche, and PHV. The effect of BMI was less consistent.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
- Otros autores: Binder A, Rojas J, Michels K, Mericq V.
- Cómo citar: Pereira A, Ferrer P, Binder A, Rojas J, Michels K, Corvalán C, Mericq V. Association between markers of adiposity during childhood and puberty onset in Latino girls. J. Clin. Endocrinol. Metab. 2023;dgad294. Online ahead of print. doi: 10.1210/clinem/dgad294. PMID: 37226986. ISSN: 0021-972X. IF [JCR]: 5.8. Q1
- Resumen: Context: Prepubertal adiposity is associated with earlier puberty. It is unclear when this association starts, if all adiposity markers are similarly associated, and whether all pubertal milestones are similarly affected.
Objective: To evaluate the association between different adiposity markers during childhood and the timing of different pubertal milestones in Latino girls.
Design, setting and participants: Longitudinal follow-up of 539 female participants of the Chilean Growth and Obesity Cohort (GOCS) recruited from childcare centers (mean age 3.5y) from the South East area of Santiago, Chile. Participants were singletons born between 2002-2003 within the normal birthweight range. Since 2006, a trained dietitian measured weight, height, waist circumference (WC) and skinfolds to estimate BMI CDC percentiles, central obesity, fat mass (%FM) and fat mass index (FMI = fat mass/height2).
Main outcome: since 2009, sexual maturation was assessed every 6 months to assess age at: i) thelarche, ii) pubarche, iii) menarche, and iv) age at peak height velocity (PHV).
Results: At thelarche, 12.5% were obese and 2% had central obesity. The median age of pubarche, menarche, and PHV were all associated with markers of adiposity at different time points during childhood; whereas thelarche only with %FM and FMI. Adiposity clusters models showed that children with trajectories of high WC, %FM and FMI during childhood were related with earlier thelarche, pubarche, menarche and PHV; BMI trajectories only with menarche and PHV.
Conclusions: Higher WC, %FM and FMI were associated with earlier age at thelarche, pubarche, menarche, and PHV. The effect of BMI was less consistent.
- Cómo citar: Pereira A, Ferrer P, Binder A, Rojas J, Michels K, Corvalán C, Mericq V. Association between markers of adiposity during childhood and puberty onset in Latino girls. J. Clin. Endocrinol. Metab. 2023;dgad294. Online ahead of print. doi: 10.1210/clinem/dgad294. PMID: 37226986. ISSN: 0021-972X. IF [JCR]: 5.8. Q1
- Resumen: Context: Prepubertal adiposity is associated with earlier puberty. It is unclear when this association starts, if all adiposity markers are similarly associated, and whether all pubertal milestones are similarly affected.
Objective: To evaluate the association between different adiposity markers during childhood and the timing of different pubertal milestones in Latino girls.
Design, setting and participants: Longitudinal follow-up of 539 female participants of the Chilean Growth and Obesity Cohort (GOCS) recruited from childcare centers (mean age 3.5y) from the South East area of Santiago, Chile. Participants were singletons born between 2002-2003 within the normal birthweight range. Since 2006, a trained dietitian measured weight, height, waist circumference (WC) and skinfolds to estimate BMI CDC percentiles, central obesity, fat mass (%FM) and fat mass index (FMI = fat mass/height2).
Main outcome: since 2009, sexual maturation was assessed every 6 months to assess age at: i) thelarche, ii) pubarche, iii) menarche, and iv) age at peak height velocity (PHV).
Results: At thelarche, 12.5% were obese and 2% had central obesity. The median age of pubarche, menarche, and PHV were all associated with markers of adiposity at different time points during childhood; whereas thelarche only with %FM and FMI. Adiposity clusters models showed that children with trajectories of high WC, %FM and FMI during childhood were related with earlier thelarche, pubarche, menarche and PHV; BMI trajectories only with menarche and PHV.
Conclusions: Higher WC, %FM and FMI were associated with earlier age at thelarche, pubarche, menarche, and PHV. The effect of BMI was less consistent.
2022
Pereira, Ana; Ferrer, Pedro
Higher prepubertal IGF-1 concentrations associate to earlier pubertal tempo in both sexes Artículo de revista
En: Horm. Res. Paediatr., 2022.
@article{nokey,
title = {Higher prepubertal IGF-1 concentrations associate to earlier pubertal tempo in both sexes},
author = {Ana Pereira and Pedro Ferrer},
doi = {doi: 10.1159/000528662},
year = {2022},
date = {2022-00-00},
urldate = {2022-00-00},
journal = {Horm. Res. Paediatr.},
abstract = {- Otros autores: Baier I, Iñiguez G, Mericq V.
- Cómo citar: Baier I, Pereira A, Ferrer P, Iñiguez G, Mericq V. Higher prepubertal IGF-1 concentrations associate to earlier pubertal tempo in both sexes. Horm. Res. Paediatr. 2022;Preprint. doi: 10.1159/000528662. PMID: 36513037. ISSN: 1663-2818. IF [JCR]: 4.275. Q1
- Resumen: Introduction: Pubertal onset is triggered by multiple neuroendocrine interactions. The role of prepubertal IGF-1 in this process has not been explored in both sexes. Our objective is to analyze the association of prepubertal IGF-1 concentration with age at thelarche (B2) and menarche (M) in girls and age at gonadarche (G2) in boys. Methods: Longitudinal study (n=1196 boys and girls) within the Growth and Obesity Chilean cohort Study (GOCS). At ages ≈ 6.7 years blood sample for IGF-1. Subjects analyzed into 4 groups according to the onset age of the pubertal event.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
- Otros autores: Baier I, Iñiguez G, Mericq V.
- Cómo citar: Baier I, Pereira A, Ferrer P, Iñiguez G, Mericq V. Higher prepubertal IGF-1 concentrations associate to earlier pubertal tempo in both sexes. Horm. Res. Paediatr. 2022;Preprint. doi: 10.1159/000528662. PMID: 36513037. ISSN: 1663-2818. IF [JCR]: 4.275. Q1
- Resumen: Introduction: Pubertal onset is triggered by multiple neuroendocrine interactions. The role of prepubertal IGF-1 in this process has not been explored in both sexes. Our objective is to analyze the association of prepubertal IGF-1 concentration with age at thelarche (B2) and menarche (M) in girls and age at gonadarche (G2) in boys. Methods: Longitudinal study (n=1196 boys and girls) within the Growth and Obesity Chilean cohort Study (GOCS). At ages ≈ 6.7 years blood sample for IGF-1. Subjects analyzed into 4 groups according to the onset age of the pubertal event.
- Cómo citar: Baier I, Pereira A, Ferrer P, Iñiguez G, Mericq V. Higher prepubertal IGF-1 concentrations associate to earlier pubertal tempo in both sexes. Horm. Res. Paediatr. 2022;Preprint. doi: 10.1159/000528662. PMID: 36513037. ISSN: 1663-2818. IF [JCR]: 4.275. Q1
- Resumen: Introduction: Pubertal onset is triggered by multiple neuroendocrine interactions. The role of prepubertal IGF-1 in this process has not been explored in both sexes. Our objective is to analyze the association of prepubertal IGF-1 concentration with age at thelarche (B2) and menarche (M) in girls and age at gonadarche (G2) in boys. Methods: Longitudinal study (n=1196 boys and girls) within the Growth and Obesity Chilean cohort Study (GOCS). At ages ≈ 6.7 years blood sample for IGF-1. Subjects analyzed into 4 groups according to the onset age of the pubertal event.